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Biomaterial supply resource
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A material supply resource that provides access to physical materials like tissue samples or organisms. For example, the IMSR enables acquisition of a transgenic mouse or cell line.
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ILX:0101300
|
3
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scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biomolecule
|
A biomolecule is any organic molecule that is produced by a living organism, including large polymeric molecules such as proteins, polysaccharides, and nucleic acids as well as small molecules such as primary metabolites, secondary metabolites, and natural products. (Wikipedia)
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ILX:0101301
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3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biophysics
|
The use of physics to study biological system.
|
ILX:0101302
|
4
|
scicrunch
|
06/11/2021
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biosensing Analyzer
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Instrumentation designed to amplify and condition the signals from a wide range of biosensors.
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ILX:0101303
|
3
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scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biosensor
|
A device for the detection of an analyte that combines a biological component with a physicochemical detector component. 1) the sensitive biological element (biological material (eg. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc), a biologically derived material or biomimic) The sensitive elements can be created by biological engineering.2) the transducer or the detector element (works in a physicochemical way; optical, piezoelectric, electrochemical, etc.) that transforms the signal resulting from the interaction of the analyte with the biological element into another signal (i.e., transducers) that can be more easily measured and quantified;3) associated electronics or signal processors that is primarily responsible for the display of the results in a user-friendly way.[2]The most widespread example of a commercial biosensor is the blood glucose biosensor, which uses the enzyme glucose oxidase to break blood glucose down. In doing so it first oxidizes glucose and uses two electrons to reduce the FAD (a component of the enzyme) to FADH2. This in turn is oxidized by the electrode (accepting two electrons from the electrode) in a number of steps. The resulting current is a measure of the concentration of glucose. In this case, the electrode is the transducer and the enzyme is the biologically active component. (from Wikipedia)
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ILX:0101304
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biospecimen repository
|
A resource that provides storage, maintenance and retrieval for biospecimen such as the Harvard brain tissue bank.
|
ILX:0101305
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biostatistics
|
From BRO: (a combination of the words biology and statistics; sometimes referred to as biometry or biometrics) is the application of statistics to a wide range of topics in biology. The science of biostatistics encompasses the design of biological experiments, especially in medicine and agriculture; the collection, summarization, and analysis of data from those experiments; and the interpretation of, and inference from, the results. - definition adapted from Wikipedia
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ILX:0101306
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biotechnology and Biological Sciences Research Council
|
The UK's leading funding agency for academic research and training in the non-clinical life sciences.
|
ILX:0101307
|
5
|
scicrunch
|
08/24/2018
|
scicrunch |
term |
12/08/2016 |
-2 |
NeuroLex |
troy sincomb |
|
Biotin
|
A member of the biotins that has formula C10H16N2O3S (CHEBI).A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. (PubChem)
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ILX:0101308
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biotin dextran
|
Dextran conjugated to biotin, used for anterograde tract tracing studies in the nervous system
|
ILX:0101309
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biperiden
|
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine. (PubChem) Pharmacology: Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control. Mechanism of action: Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of action of centrally active anticholinergic drugs such as biperiden is considered to relate to competitive antagonism of acetylcholine at cholinergic receptors in the corpus striatum, which then restores the balance. Drug type: Approved. Small Molecule. Drug category: Antidyskinetics. Antiparkinson Agents. Muscarinic Antagonists. Parasympatholytics
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ILX:0101310
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Biphetamine
|
|
ILX:0101311
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Bipolar Cell Morphology
|
|
ILX:0101312
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Bipolar dendrite neuron
|
Multidendritic neuron with bipolar dendrites that grow in opposite directions without major side branches. These neurons are located inside the body and are often associated with muscles.
|
ILX:0101313
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Bipolar Disorder
|
A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence (MeSH).
|
ILX:0101314
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Bipolar neuron of Bolwig nerve
|
|
ILX:0101315
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Bipolar Progenitor Cell
|
A type of NG2 positive cell that resemble oligodendrocyte precursors
|
ILX:0101316
|
4
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Birmingham object recognition battery
|
a set of standardized procedures for assessing neuropsychological disorders of visual object recognition which includes tests to assess low-level aspects of visual perception (using same-different matching of basic perceptual features, such as orientation, length, position and object size), intermediate visual processes (e.g., matching objects different in viewpoint), access to stored perceptual knowledge about objects (object decision), access to semantic knowledge (function and associative matches) and access to names from object (picture naming).
|
ILX:0101317
|
4
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
BIRN-INCF Derived Data Project
|
The Derived Data Working Group is focused on understanding, addressing and solving the known difficulties of sharing and combining data across multiple sites after post-processing and/or data analysis. This WG is working closely with researchers at UC Irvine, Columbia, Duke, MIT, MRN and INCF on these goals:-Develop provenance and derived data extraction scripts for common neuroimaging analysis software and pipelines-Extend tools and specifications for international community requirements-Create/curate an initial neuroimaging terminology and ontology for derived data and common neuroimaging concepts-Augment/improve derived data import and query functionality for multi-site derived data federationsNeuroimaging data often involves many aspects of image and signal processing on the raw data which takes considerable time and expertise. Making such derived data available in a structured and well documented way is of interest to the international neuroimaging community. The availability of large multi-site datasets such as the Function BIRN schizophrenia datasets and the 1000 Functional Connectomes Project data provides researchers with well-documented and structured raw data. The addition of a similarly well-documented and structured form for derived data is the focus of this working group. Although the Function BIRN had made strides in developing the XCEDE XML schema for the structured storage and interchange of neuroimaging derived data, being able to extract both the derived results and the provenance of what happened to the data during the analytical manipulations directly from the software and pipelines performing the computations is missing. Without this piece, documenting derived data provenance and results becomes a burden on the researchers who are more interested in addressing scientific hypotheses than in documenting who the result was obtained for other users.To address the needs for providing derived data to the public community we have formed the derived data working group. This group brings together researchers with extensive experience with neuroimaging studies and specifically with large-scale data analysis and management using the more prevalent software packages in the field, e.g. SPM and FSL. This working group leverages the experience of the group both within BIRN and in communication with other researchers through the INCF to identify information needed for a provenance description to be useful. Face-to-face meetings to discuss needs and possible approaches were held in 2011 and 2012 at UC Irvine in January, at OHBM in June 2011, at the INCF Standards for Data Sharing task force meeting in September, and a fourth meeting in November at the annual meeting for the Society for Neuroscience.Once these details are established and there is consensus among the community, we will address the format for which this information will be stored. Initially we are focusing on XML schemas that integrate with the existing XCEDE XML schema (W3C Prov model) which describes neuroimaging data sets in general. After identifying the needed pieces of information and their storage format we will both work with the developers of the software packages to integrate the provenance schemas into their distributions or where not possible, write scripts to extract the information. All products of the derived data group are open-source and freely available to the community through the BIRN public wiki and INCF GitHub repositories.
|
ILX:0101318
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Bisoprolol
|
A cardioselective beta-1-adrenergic blocker. It is effective in the management of hypertension and angina pectoris. (PubChem) Pharmacology: Bisoprolol is a competitive, beta(1)-selective (cardioselective) adrenergic antagonist. Bisoprolol is used to treat hypertension, arrhythmias, coronary heart disease, glaucoma, and is also used to reduce non-fatal cardiac events in patients with heart failure. Activation of beta(1)-receptors (located mainly in the heart) by epinephrine increases the heart rate and the blood pressure, and the heart consumes more oxygen. Drugs such as Bisoprolol that block these receptors therefore have the reverse effect: they lower the heart rate and blood pressure and hence are used in conditions when the heart itself is deprived of oxygen. They are routinely prescribed in patients with ischemic heart disease. In addition, beta(1)-selective blockers prevent the release of renin, which is a hormone produced by the kidneys which leads to constriction of blood vessels. Bisoprolol is lipophilic and exhibits no intrinsic sympathomimetic activity (ISA) or membrane stabilizing activity. Mechanism of action: Bisoprolol selectively blocks catecholamine stimulation of beta(1)-adrenergic receptors in the heart and vascular smooth muscle. This results in a reduction of heart rate, cardiac output, systolic and diastolic blood pressure, and possibly reflex orthostatic hypotension. Bisoprolol can also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles, causing bronchospasm. Drug type: Approved. Small Molecule. Drug category: Adrenergic Agents. Adrenergic beta-Antagonists. Antihypertensive Agents. Sympatholytics
|
ILX:0101319
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |