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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Behavioral neuropharmacology Branch of neuropharmacology dealing with behavior. ILX:0101200 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Behavioral process ILX:0101201 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Behavioral quality A monadic quality of continuant inhering in a bearer by virtue of its behavior. ILX:0101202 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Behavioral quality of a process A monadic quality of occurrent inhering in a bearer by virtue of its behavior. ILX:0101203 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Behavioral rating inventory of executive function used for evaluating and planning treatment strategies for a wide spectrum of developmental and acquired neurological conditions, including learning disabilities, low birth weight, ADHD, Tourette's disorder, Traumatic Brain Injury, and Autism; consists of 8 non-overlapping clinical scales that form two broader indexes: Behavior Regulation (three scales) and Metacognition (five scales). A Global Executive Composite score is also produced; completed by parents and teachers, is suitable for children as young as 5 years old. ILX:0101204 5 scicrunch 09/07/2018 scicrunch term 12/08/2016 0 NeuroLex troy sincomb
Behavioral science From BRO: Behavioural science (or Behavioral science) is a term that encompasses all the disciplines that explore the activities of and interactions among organisms in the natural world. It involves the systematic analysis and investigation of human and animal behaviour through controlled and naturalistic experimental observations and rigorous formulations. (E. D. Klemke, R. Hollinger, and A. D. Kline, (ed) (1980)) - definition adapted from Wikipedia ILX:0101205 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Behavioral system function ILX:0101206 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benazepril Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor. Pharmacology: Benazepril, an angiotensin-converting enzyme (ACE) inhibitor, is a prodrug which, when hydrolyzed by estarases to its active Benazeprilat, is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Benazepril and Benazeprilat inhibit angiotensin-converting enzyme (ACE) in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. Mechanism of action: Benazeprilat, the active metabolite of Benazepril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blood pressure and stimulation of baroreceptor reflex mechanisms, which leads to decreased vasopressor activity and to decreased aldosterone secretion. Benazeprilat may also act on kininase II, an enzyme identical to ACE that degrades the vasodilator bradykinin. Drug type: Approved. Investigational. Small Molecule. Drug category: Angiotensin-converting Enzyme Inhibitors. Antihypertensive Agents ILX:0101207 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benchmark A resource used to assess the relative performance of an object, normally by running a number of standard tests and trials against it. The term 'benchmark' is also mostly utilized for the purposes of elaborately-designed benchmarking programs themselves. Benchmarks provide a method of comparing the performance of various subsystems across different tools. Adapted from Wikipedia. ILX:0101208 5 scicrunch 08/24/2018 scicrunch term 12/08/2016 0 NeuroLex troy sincomb
Benchmarking dataset Benchmarking is the process of comparing the cost, cycle time, productivity, or quality of a specific process or method to another that is widely considered to be an industry standard or best practice. ILX:0101209 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Bendroflumethiazide A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810) Pharmacology: Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue. Mechanism of action: As a diuretic, bendroflumethiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like bendroflumethiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter. This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. The antihypertensive mechanism of bendroflumethiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle. Drug type: Approved. Small Molecule. Drug category: Antihypertensive Agents. Diuretics. Diuretics, Thiazide. Sodium Chloride Symporter Inhibitors ILX:0101210 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benign essential blepharospasm A progressive neurological disorder characterized by involuntary muscle contractions and spasms of the eyelid muscles. It is a form of dystonia, a movement disorder in which muscle contractions cause sustained eyelid closure, twitching or repetitive movements. BEB begins gradually with increased frequency of eye blinking often associated with eye irritation. Other symptoms may include involuntary winking or squinting of one or both eyes, increasing difficulty in keeping the eyes open, and light sensitivity. Generally, the spasms occur during the day, disappear in sleep, and reappear after waking. As the condition progresses, the spasms may intensify, forcing the eyelids to remain closed for long periods of time, and thereby causing substantial visual disturbance or functional blindness. It is important to note that the blindness is caused solely by the uncontrollable closing of the eyelids and not by a dysfunction of the eyes. BEB occurs in both men and women, although it is especially common in middle-aged and elderly women. (NINDS Disorder Index, http://www.ninds.nih.gov/disorders/blepharospasm/blepharospasm.htm) ILX:0101211 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benign Neonatal Epilepsy A condition marked by recurrent seizures that occur during the first 4-6 weeks of life despite an otherwise benign neonatal course. Autosomal dominant familial and sporadic forms have been identified. Seizures generally consist of brief episodes of tonic posturing and other movements, apnea, eye deviations, and blood pressure fluctuations. These tend to remit after the 6th week of life. The risk of developing epilepsy at an older age is moderately increased in the familial form of this disorder (MeSH). ILX:0101212 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Bent Shape which has one or more angle(s) in a length of a bearer entity. ILX:0101213 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Bentiromide Bentiromide is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is given by mouth as a noninvasive test. The amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. Headache and gastrointestinal disturbances have been reported in patients taking bentiromide. Bentiromide is not available in the U.S. or Canada (It was withdrawn in the US in October 1996). Pharmacology: Bentiromide is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is given by mouth as a noninvasive test. The amount of p-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. Headache and gastrointestinal disturbances have been reported in patients taking bentiromide. Bentiromide is not available in the U.S. or Canada. Mechanism of action: Bentiromide is a peptide that is broken down in the pancreas by lipase, protease, and amylase. By determining the output of unchanged bentiromide in the urine following oral administration, it is possible to determine the sufficiency of pancreatic activity. Drug type: Approved. Small Molecule. Drug category: Diagnostic aids. Indicators and Reagents ILX:0101214 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benton facial recognition test A tool used to assess deficits in facial recognition. ILX:0101215 6 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Bentoquatam Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin. Pharmacology: Bentoquatam protects the skin like a shield against poison ivy, poison oak, and poison sumac by physically blocking skin contact with their resin. The best protection against getting these conditions is to avoid contact with these plants. This medicine does not dry oozing and weeping caused by the rash of poison ivy, poison oak, or poison sumac. Mechanism of action: The mechanism of action is unknown. It is thought topically applied bentoquatam acts as a physical barrier that interferes with the adsorption of antigens onto the skin and reduces absorption of antigens into the skin. It probably does not work by modifying the systemic allergic response. Drug type: Approved. Small Molecule. Drug category: Skin protectant, barrier (topical) ILX:0101216 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benzedrine The trade name of the racemic mixture of amphetamine (dl-amphetamine) and marketed in the form of inhalers. Benzedrine was used to enlarge nasal and bronchial passages and it is closely related to other stimulants, such as dextroamphetamine (d-amphetamine) and methamphetamine. While the drug was initially used for medical purposes, as a bronchodilator, early users of the Benzedrine inhaler discovered that it had a euphoric stimulant effect, resulting in it being one of the earliest synthetic stimulants to be widely used for recreational (i.e., non-medical) purposes.(Adapted from Wikipedia) ILX:0101217 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benzene Organic Compound;Solvent;Gasoline Additive/Component;Industrial Precursor/Intermediate;Aromatic Hydrocarbon; Benzene is an aromatic hydrocarbon formed both naturally and from human activities. It can be found in crude oil, gasoline, and cigarette smoke, and made mostly from petroleum sources. Benzene is a highly flammable, colorless liquid with a sweet odor. ILX:0101218 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Benzidine Organic Compound;Aromatic Hydrocarbon;Amine; Benzidine is a manufactured chemical that does not occur naturally. In the environment, benzidine is found either as an organic base or as a salt. Benzidine was used to produce dyes for cloth, paper, and leather, but is no longer produced or used commerically due to its carcinogenicity. ILX:0101219 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex

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