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Total 393357 Results

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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Dendronotina ILX:0103034 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dendronotoidea ILX:0103035 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus ILX:0103036 6 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus dalli ILX:0103037 6 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus frondosus ILX:0103038 6 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus iris ILX:0103039 6 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Denileukin diftitox A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system. Pharmacology: Denileukin diftitox (Ontak) directs the cytocidal action of diphtheria toxin to cells which express the IL-2 receptor. The human IL-2 receptor exists in three forms, low (CD25), intermediate (CD122/CD132) and high (CD25/CD122/CD132) affinity. Malignant cells expressing one or more of the subunits of the IL-2 receptor are found in certain leukemias and lymphomas including cutaneous T-cell lymphoma (CTCL). Ontak interacts with the high affinity IL-2 receptor on the cell surface and inhibits cellular protein synthesis, resulting in cell death within hours. Mechanism of action: Denileukin diftitox binds to the high-affinity IL-2 receptor complex. The IL-2 receptor (Tac) subunit is expressed on activated but not resting lymphocytes. The diphtheria toxin associated with Ontak then selectively kills the IL-2 bearing cells. Drug type: Approved. Biotech. Investigational. Drug category: Antineoplastic Agents ILX:0103040 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dense A physical quality which inheres to the bearer by virtue of some influence exerted by its mass. ILX:0103041 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dense Body An electron dense body, some of which contain granules (Peters, Palay and Webster (1991) ILX:0103042 9 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dense Core Vesicle 40-60 nm vesicle containing an electron dense granule, 15-20 nm in diameter (Peters, Palay and Webster, 1991). ILX:0103043 9 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dense Material Electron dense material visible between the lamellae of the spine apparatus ILX:0103044 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Density ILX:0103045 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Density (PATO 0001019) A physical quality which inheres to the bearer by virtue of some influence exerted by its mass. ILX:0103046 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Densocellular part of medial dorsal nucleus ILX:0103047 10 scicrunch 06/23/2020 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dentate gyrus axo-axonic cell ILX:0103049 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dentate gyrus basket cell ILX:0103050 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dentate gyrus crest granule cell layer of ABA 2009 ILX:0103051 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dentate gyrus crest molecular layer of ABA 2009 ILX:0103052 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dentate gyrus crest of ABA 2009 ILX:0103053 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Dentate gyrus crest polymorph layer of ABA 2009 ILX:0103054 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex

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