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Total 393357 Results

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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
CXCL6 ILX:0102712 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCL7 ILX:0102713 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCL8 ILX:0102714 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCL9 ILX:0102715 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCR1 receptor ILX:0102716 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCR2 receptor ILX:0102717 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCR3 receptor ILX:0102718 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCR4 receptor ILX:0102719 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
CXCR5 receptor ILX:0102720 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyan A Cyan is a flow_cytometer_analyser manufactured by Dako Cytomation. It features include digital electronics, three lasers: 488 nm, 635 nm, and 405 nm, and filters and collectors for nine fluorescent parameters and two scatter parameters. The Cyan can be used for measuring the properties of individual cells. ILX:0102721 4 scicrunch 06/12/2021 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyan fluorescent protein ILX:0102722 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyanide Organic Compound;Cyanide Compound;Nitrile; Certain bacteria, fungi, and algae can produce cyanide, and cyanide is found in a number of foods and plants. Cyanides also occur naturally as part of sugars or other naturally-occurring compounds. ILX:0102723 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyanocobalamin Cyanocobalamin (commonly known as Vitamin B12) is the most chemically complex of all the vitamins. Cyanocobalamin's structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Cyanocobalamin cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Cyanocobalamin is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products. (HMDB) Pharmacology: Cyanocobalamin (Vitamin B12) is a water-soluble organometallic compound with a trivalent cobalt ion bound inside a corrin ring. It is needed for nerve cells and red blood cells, and to make DNA. Vitamin B12 deficiency is the cause of several forms of anemia. Mechanism of action: Vitamin B12 is used in the body in two forms: Methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells. Drug type: Approved. Nutraceutical. Small Molecule. Drug category: Antianemic Agents. Essential Vitamin. Vitamins (Vitamin B Complex) ILX:0102724 4 scicrunch 08/24/2018 scicrunch term 12/08/2016 0 NeuroLex troy sincomb
Cyclacillin A cyclohexylamido analog of penicillanic acid. (PubChem) Pharmacology: Cyclacillin, a penicillin, is a cyclohexylamido analog of penicillanic acid. Cyclacillin is more resistant to beta-lactamase hydrolysis than ampicillin, is much better absorbed when given by mouth and, as a result, the levels reached in the blood and in the urine are considerably higher than those obtained with the same dose of ampicillin. Cyclacillin has been replaced by newer penicillin treatments. Mechanism of action: The bactericidal activity of cyclacillin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cyclacillin is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases. Drug type: Approved. Small Molecule. Drug category: Anti-Bacterial Agents. Penicillins ILX:0102725 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyclic-nucleotide gated channel ILX:0102726 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyclic-nucleotide gated channel - type A ILX:0102727 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyclic-nucleotide gated channel - type B ILX:0102728 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyclin-dependent kinase 5 serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression (from Rat Genome Database) ILX:0102729 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyclin-dependent kinase 5 regulatory subunit 1 A protein that serves as a neuron-specific activator of cyclin-dependent kinase 5 (CDK5)(from Entrez gene) ILX:0102730 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Cyclizine A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935) Pharmacology: Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects. Mechanism of action: Vomiting (emesis) is essentially a protective mechanism for removing irritant or otherwise harmful substances from the upper GI tract. Emesis or vomiting is controlled by the vomiting centre in the medulla region of the brain, an important part of which is the chemotrigger zone (CTZ). The vomiting centre possesses neurons which are rich in muscarinic cholinergic and histamine containing synapses. These types of neurons are especially involved in transmission from the vestibular apparatus to the vomiting centre. Motion sickness principally involves overstimulation of these pathways due to various sensory stimuli. Hence the action of cyclizine which acts to block the histamine receptors in the vomiting centre and thus reduce activity along these pathways. Furthermore since cyclizine possesses anti-cholinergic properties as well, the muscarinic receptors are similarly blocked. Drug type: Approved. Small Molecule. Drug category: Antiemetics. Histamine H1 Antagonists. Piperazine Derivatives ILX:0102731 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex

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