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Total 393357 Results
| Label | Description | ILX | Version | Created CID | Modified Time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Citation record element | Those elements defined as a part of the PubMed DTD and used by many literature citation databases | ILX:0102204 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| CIVM postnatal rat brain atlas parcellation scheme | Parcellation scheme for the CIVM postnatal rat brain atlas, designed as a developmental neuro-ontology for tracking regional changes in MR biomarkers throughout postnatal neurodevelopment. | ILX:0102205 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| CIVM postnatal rat brain atlas parcellation scheme region | Brain regions defined in the CIVM postnatal rat brain atlas parcellation scheme and criteria for their identification in MRI images | ILX:0102206 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Cladodromous | A shape inhering in a bearer by virtue of having secondary branches freely branching toward the margin. | ILX:0102207 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Cladribine | An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia. (PubChem) Pharmacology: Cladribine is a synthetic antineoplastic agent with immunosuppressive effects. Cladribine is one of a group of chemotherapy drugs known as the anti-metabolites.Anti-metabolites stop cells making and repairing DNA. Cancer cells need to make and repair DNA in order to grow and multiply. Mechanism of action: Cladribine is structurally related to fludarabine and pentostatin but has a different mechanism of action. It is phosphorylated to its corresponding nucleotide CdATP, which accumulates and is incorporated into the DNA of cells such as lymphocytes. High levels of CdATP lead to DNA strand breaks, inhibition of DNA synthesis, and cell death. Unlike other antimetabolite drugs, cladribine has cytotoxic effects on resting as well as proliferating lymphocytes. However, it does cause cells to accumulate at the G1/S phase junction, suggesting that cytotoxicity is associated with events critical to cell entry into S phase. It also binds purine nucleoside phosphorylase (PNP), however no relationship between this binding and a mechanism of action has been established. Drug type: Approved. Investigational. Small Molecule. Drug category: Antineoplastic Agents. Immunosuppressive Agents | ILX:0102208 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Clarithromycin | A semisynthetic macrolide antibiotic derived from erythromycin that is active against a variety of microorganisms. It can inhibit protein synthesis in bacteria by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation. (PubChem) Pharmacology: Clarithromycin, a macrolide antibiotic similar to erythromycin and azithromycin, is effective against Mycobacterium avium complex (MAC) and is used for the treatment of Helicobacter pylori-associated peptic ulcer disease, community-acquired pneumonia, sinusitis, and chronic bronchitis. Clarithromycin is also used to treat respiratory tract, sexually transmitted, otitis media, and AIDS-related infections. Mechanism of action: Clarithromycin is first metabolized to 14-OH clarithromycin. Like other macrolides, it then binds to the 50 S subunit of the 70 S ribosome of the bacteria, blocking RNA-mediated bacterial protein synthesis. Clarithromycin also inhibits the hepatic microsomal CYP3A4 isoenzyme and P-glycoprotein, an energy-dependent drug efflux pump. Drug type: Approved. Small Molecule. Drug category: Anti-Bacterial Agents. Macrolides. Other Macrolides. Protein Synthesis Inhibitors | ILX:0102209 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Clarity | A method for the transformation of intact tissue into a nanoporous hydrogel-hybridized form (crosslinked to a three-dimensional network of hydrophilic polymers) that is fully assembled but optically transparent andmacromolecule-permeable. | ILX:0102210 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Clark WELeG 1951 Parcellation scheme | Parcellations or definitions of nervous system structures from Clark WELeG (1951): Central nervous system. In Cunningham's Text-Book of Anatomy, 9th edn, ed Brash JC (Oxford University Press, London), pp 835-1008. | ILX:0102211 | 5 | scicrunch | 08/24/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Clark WELeG 1951 Parcellation scheme region | Nervous system structure definitions from Clark WELeG (1951): Central nervous system. In Cunningham's Text-Book of Anatomy, 9th edn, ed Brash JC (Oxford University Press, London), pp 835-1008. | ILX:0102212 | 5 | scicrunch | 08/24/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Clarke's Nucleus | A rounded collection of cells locat4ed on the medial surface of the base of the posterior horn. Considered by many to be a part of the posterior horn. Two column-shaped nuclear masses formed by large cells. Clarke's nuclei are located in the regions dorsolateral to the central canal in the thoratic and upper lumbar segments. | ILX:0102213 | 17 | scicrunch | 03/11/2021 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Class 1 small leucine-rich proteoglycan | A protein with a core domain composition consisting of eight to ten tandem leucine-rich repeat sequences that are flanked at either end by cysteine rich disulfide loops. [PMID:14562268] | ILX:0102214 | 7 | scicrunch | 10/24/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Class I dendritic arborizing neuron | A dendritic arborizing md sensory neuron with a long, dorsally directed primary dendrite which branches repeatedly along its length into antero-posteriorly oriented secondary dendrites. The dendrites are smooth and their branching pattern is relatively simple, with few side branches or varicosities. | ILX:0102215 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Class II dendritic arborizing neuron | A dendritic arborizing md sensory neuron with multiple long and sinuous dendrites. Their branching pattern is relatively symmetrical. Higher order branches are generally short stubs extending from the major trunks. | ILX:0102216 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Class III dendritic arborizing neuron | A dendritic arborizing md sensory neuron with long primary and secondary dendrites that have spiked protrusions along most of their length and at the ends of major branches. | ILX:0102217 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Class IV dendritic arborizing neuron | A dendritic arborizing md sensory neuron with a highly complex branching pattern that completely fills large regions of the body wall with its arbors. Each cell may have 800-900 terminal branches and more than 6 branch orders. | ILX:0102218 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Class project | A project conducted by students as part of a course or program of study. | ILX:0102219 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Classic Globoid Cell Leukodystrophy | ILX:0102220 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Classic Pelizaeus-Merzbacher Disease | ILX:0102221 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Classical conditioning | Subjects are presented with paired stimuli in an attempt to study associative learning or get a subject to react to the conditioned stimulus in the same manner as the unconditioned stimulus, demonstrating a learned association between the two. | ILX:0102222 | 4 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Classical conditioning paradigm | A behavioral paradigm in which subjects are presented with paired stimuli (usually involving presentation of an eye puff with an auditory tone) in an attempt to study associative learning. | ILX:0102223 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
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